Faculdade de Ciências e Tecnologia
Departamento de Ciências da Vida
Teacher in charge
José Ricardo Ramos Franco Tavares, Pedro Miguel Ribeiro Viana Baptista
The main purpose of this course is to raise awareness towards the increasing relevance of nanotechnology, with particular emphasis on nanotechnology in biomedical applications.
In particular, it is intended to stimulate the students’ understanding of concepts and underlying mechanisms of nanotechnology applications in biodiagnostics and construction of biosensors, within a broader field of developments in clinical diagnostics and biomedicine research.
Historic perspective on the origin of Nanotechnology
Scale effect and properties of nanomaterials.
Nanofabrication: bottom-up vs. top-down approach
Microscopy for nanomaterials characterisation (TEM, SEM, SPR)
Bionanotechnology and Bionanomachines
Nanoparticles for clinical applications
Nanotechnology and Green Chemistry
Construction of nanostructures
DNA based nanostructures
Protein based nanostructures
DNA & RNA (cross-linking vs. non-cross-linking)
Nanoparticles for drug delivery and nanovectors for gene therapy.
C.M. Niemeyer, C.A. Mirkin (Eds.), 2004, Wiley-VCH, Weinhein, Germany
B.D. Fahlman, 2007, Springer, Dordrecht, the Netherlands
“Bionanotechnology”, D.S. Goodsell, 2004, Wiley-Liss, Hoboken, NJ, USA
Theoretical classes of exposition with 2 h duration, includign problem solving. Practical laboratory classes with 3 h duration that include the laboratory implementation and accomplishment of protocols and a written report.
Reports of the practical sessions (25% of the final grade)
Papers presentation and discussion (10% of the final grade)
Monograph of selected themes (45% of the final grade) and oral presentation (20% of the final grade)