NOVA Medical School | Faculdade de Ciências Médicas





Cardiopneumology teaching area of ESSCVP



Teacher in charge

Hélder Joaquim Soares da Cruz

Teaching language

Portuguese / English


It is intended for students to apprehend general concepts of two features of bioengineering, with great utility in Cardiopneumology: the bioengineering as electronics and the bioengineering of cells and tissues.

The attention is focused on the comprehension of the physiological signal transduction, giving an overview of the functioning of the main equipment used in Cardiopneumology, as this is a central area of the degree and of practical application.

On the subject of bioengineering of cells and tissues, it is intended for students to apprehend general concepts as well as methods and techniques of characterization, culture and differentiation of stem cells in particular. It is also intended to discuss important aspects of the applications of stem cells in cellular therapy and regenerative medicine, whose use in the context of Cardiopneumology, now a reality, is expected to be widely applied in the near future.



Subject matter

• General concepts of bioengineering, namely, general principles of conception and functioning of the main clinical equipment’s (ECG, Pulse Oximeter, among others);

• Principles of signal transduction. Definition of a typical chain of acquisition and signal processing. Concepts and functional blocks of electronic and functioning of clinical equipment: amplifiers, AD / DA converters, filtering. Basic knowledge of pattern recognition;

• General concepts of bioengineering of cells and tissues, namely types of cells, culture systems, media and supplements, modes of operation;

• Definitions of types of stem cells, existing sources, degrees of differentiation, plasticity, culture methods, characterization and applications, with emphasis on cellular therapy and regenerative medicine;

• Concepts and advanced techniques of collection, isolation, culture, differentiation and characterization of stem cells in the context of therapy.


- Gregg, R. , Zhou, S. , Lindauer, J., Helfenbein, E. , and Giuliano, K., What is inside the electrocardiograph, Journal of Electrocardiology, Volume 41, Issue 1, January-February 2008, Pages 8-14.


- McClellan, J., Schafer, R. and Yoder, M, DSP FIRST: A Multimedia Approach. Prentice Hall, Upper Saddle River, New Jersey, 1998. Copyright (c) 1998 Prentice Hall.


- Chung, E., Pocket Guide to ECG Diagnosis, 2nd Edition, ISBN: 978-0-86542-589-7, Wiley-Blackwell.


- Stem Cells and the Future of Regenerative Medicine, Committee on the Biological and Biomedical Applications of Stem Cell Research, Board on Life Sciences National Research Council, Board on Neuroscience and Behavioral Health Institute of Medicine, NATIONAL ACADEMY PRESS, Washington, D.C.


- Hyun, I., Lindvall, O., Ährlund-Richter, L., et al. (2008). New ISSCR Guidelines Underscore Major Principles for Responsible Translational Stem Cell Research. Cell Stem Cell 3, 607-610.

Teaching method

The teaching methodology is based on theoretical classes, with concepts, definitions and techniques, involving effective and attractive audiovisual technologies, with theoretical-practical classes where subjects will be related to real and practical examples, to be presented in an interactive manner and inviting students to actively participate, encouraging a critical discussion.

Evaluation method

The evaluation will have an individual component and a component of group work.